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M4I

Maastricht MultiModal Molecular Imaging Institute

The Maastricht MultiModal Molecular Imaging Institute (M4I) is a state-of-the art molecular imaging institute that brings together a powerful palette of high-end, innovative imaging technologies. The mission of the institute is to perform fundamental, instrumentation and applied studies in molecular imaging as a part of a translational, synergistic, interdisciplinary research programme. M4I aims to be a leading international molecular imaging center relevant for science, education, economy and society. The institute aspires to generate a high-end research environment and a unique knowledge infrastructure, attractive to top researchers from all over the world.

Research

The M4I Division of Nanoscopy investigates cell structures at a macromolecular level. Inside cells, proteins work together in complex structures and are responsible for virtually all processes in the human body, including diseases such as cancer. To understand the working mechanisms of protein complexes, three-dimensional imaging of normal and disease-causing protein complexes is essential. This could ultimately lead to more effective treatments, but also to vaccines against diseases such as tuberculosis.

The M4I Division of Imaging Mass Spectrometry is one of the world leaders in high resolution molecular imaging of biological surfaces. The division targets the development and application of state-of-the-art mass spectrometry based molecular imaging approaches for biomedical cellular and tissue research. Main research aim for the coming years is to develop and apply mass spectrometry as a diagnostic and prognostic tool for personalized medicine.