Maastricht Centre for Systems Biology

The primary aim of the Maastricht Centre for Systems Biology (MaCSBio) is to facilitate the integration of biological data coming from several empirical domains using mathematical multi-scale modelling approaches. The centre is a joint initiative of the Faculty of Psychology & Neuroscience, Faculty of Health, Medicine & Life Sciences, and Faculty of Humanities and Sciences.

NeuGenNet is a multidisciplinary research programme with the overall goal of achieving new insights into the processes of normal and abnormal experience-induced modifications in brain and genetic networks, using mathematical tools and modeling approaches to bridge research domains and spatial scales of inquiry.

The aim of SYSTOPP is to develop new systems biology multi-level models and approaches to modelling, in order to establish biology-based personalized risk profiles for chronic diseases (type 2 diabetes, cardiovascular disease, cancer) in the overweight/obese. We are mainly interested in the integration of large, multi-omics data from various cohort studies with statistical, genome scale metabolic, and dynamic models.

Teaching takes place in the two-year master's programme Systems Biology. There you acquire the knowledge and practical skills necessary for unravelling the complexity of biological systems, to bridge biology and mathematics from molecule to ecosystem, and to translate and integrate large and heterogeneous datasets into biologically relevant information and experiments.